Leading the way in microbiome research

The International Microbiome Centre at the University of Calgary is a translational research centre, designed to investigate the microbiome of humans, plants, animals and the physical environment. Together, world class microbiome researchers, advanced technologies and relationship building will spark groundbreaking discoveries that harness the healing power of the microbiome.

The International Microbiome Centre is made up of
research platforms that aim to:

Heart

Find new and better ways to diagnose and treat many health issues.

Trash

Decrease food waste and production problems

Polution

Explore how microbiomes can have a positive impact on environmental health

Solving these challenges can have major, lasting change.
For the economy, the environment and world health.

Featured Platforms

In the news


Gut reaction: How the gut microbiome may influence the severity of COVID-19

Community of micro-organisms performs many beneficial functions, write Shirin Moossavi and Marie-Claire Arrieta, Cumming School of Medicine, in Conversation Canada...

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Who are you? Event guests take a quiz to learn more about their microbiomes

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UCalgary receives new funding that will support breakthroughs in the vital area of microbiome research

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UCalgary scholars share expertise with French colleagues on parasite protection, stress transmission, and why we eat

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Explore all the platforms

The 10,000-square-foot germ-free facility provides researchers with mice born under germ-free conditions. And it’s the only facility that can image every organ of an animal in real time under germ free conditions. Researchers introduce selected bacteria to the mice and study their effects on the microbiome and it could be the key to understanding how to prevent and treat chronic illness.

Our imaging platform is creating new and transformational opportunities for discovery. Real-time in vivo and in vitro imaging of the microbiome allows us to:

  • study it under changing environments
  • explain host-microbiome interaction
  • understand how the microbiome maintains health and causes diseases

The phenomics platform provides expertise in non-invasive whole body imaging to assess drug mechanism, distribution and impact in models of chronic disease.

Bioinformatics is where computer science and molecular biology meet. Using it to analyze and interpret biological data helps us:

  • understand the genetic basis of diseases
  • identify microbial species and their properties
  • find differences between populations

This platform supports researchers by supplying innovative information on metabolite profiles related to the microbiome. Research will focus on identifying the genes, proteins, and metabolites associated with diseases and understanding their genetic basis. Together, these technologies will allow us to identify new targets in diagnosis and drug development.

Mass cytometry is used to identify new biomarkers, and identify cell types in normal and disease states. It allows us to fingerprint a single cell, which is important for research in immunology, hematology, oncology, and other fields.

There are several applications, including quantitative and qualitative deep profiling of immune cells. It’s also expected to have a major impact on drug development and disease diagnosis.

The IMC biobanking facility provides access to specialized technology services and training for microbiome biobanking of bacteria, patient samples, and strains from chronic disease sufferers.

Data obtained from biobanking samples supports many types of critical research, including genomics and personalized medicine.

The International Microbiome Centre (IMC) Advanced Imaging and Biomarker Discovery platform is a state-of-the-art program that provides access to and expertise in advanced technologies (MIBI) for visualizing immune cells and microbes using high parameter analysis and spatial positioning within tissues. 

Projects

The International Microbiome Centre (IMC) at the University of Calgary is a translational research centre, designed to investigate the microbiome of plants, animals and the physical environment.

diet

What is the connection between the microbiome and your diet?

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ecology

Ecology of the human early life microbiome

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asthma

The early-life microbiome in asthma development

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bacteria

It's not just bacteria, is it?

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BLOOM

Alberta BLOOM study: Begin a life of health with observation and optimization of the microbiome

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immune system

The immune system and the microbiome

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oil sands

Exploring oil sands could be the key to developing new bug-killing drugs

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bacteria

Balancing the body's bacteria

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autism

Changing the course of autism in newly diagnosed cases by FMT.

A study of the possible microbial links with neurodevelopmental disorders.

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immunity and disease

What is the microbiome's role in immunity and disease?

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microbat

How does the interaction

between intestinal microbiota and the immune system affect health and diseases?

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